Sensors and Instrumentation and Nondestructive Evaluation
Biomedical Applications
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Medical Ice Slurry Coolants for Inducing Targeted-Organ/Tissue Protective Cooling
by
Dr. Ken Kasza, PhD et al.
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full article [
542KB]
Technology Description
Figure 1 shows a research version of the Argonne-developed system for making an ice slurry. The produced slurry has the following attributes:
- Small ice particles (<0.1 millimeter),
- High ice concentration (>50 weight percent),
- Biologically compatible carrier liquid (saline solution plus other ingredients),
- Several times the cooling capacity of water (ice = 80 cal/g°C versus water = 1 cal/g°C),
- Excellent fluidity and storability obtained by altering ice particle size, shape, and surface roughness by using patented methods, and
- Slurry that can be pumped nearly as easily as water through very small, properly designed delivery devices.
Figure
1: Argonne-Developed Equipment for Making and Delivering Medical Slurry
Click on photo to view a larger image.
The slurry production equipment in Figure 1:
- Produces slurry on-demand (< 2 min processing time),
- Is portable,
- Uses disposable sterile ingredient modules,
- Has a controllable dose and delivery rate,
- Is capable of continuous or intermittent delivery,
- Can maintain protective cooling for > 2 hours, and
- Includes special delivery injectors developed for various medical uses.
Medical Ice Slurry Coolants for Inducing Targeted-Organ/Tissue Protective
Cooling
Next page: Application in Advanced Laparoscopic Procedures
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Multimedia
Laparoscopic
Partial Nephrectomy with Ice Slurry as Coolant in the Porcine Model
This video depicts the usage of ice slurry cooling, using a porcine model, for protecting the kidney from ischemia damage during a partial nephrectomy. The video illustrates the ease of use, protective benefits and advantages of using slurry cooling over cold saline solution.
Read full story and watch video
Computer
model of a kidney being cooled by ice slurry
Computer model of a kidney being cooled by ice slurry (model created with ABAQUS code)
Watch video
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In the Press
- "Rapid cooling technology
could aid surgery patients, heart attack victims"
Argonne News Release (Oct. 31, 2008)
Related Media Coverage: R&D magazine, medGadget, CARG blog, PhysOrg.com, Forbes, U.S. News & World Report, Discovery Channel, The University of Chicago, Chicago Tribune, Medill Reports Chicago -
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BioTime Press Releases (Nov. 2, 2007) - ReachMD - Radio interview (REGISTRATION NEEDED to listen/download podcast)
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Argonne logos, Spring 2003
Last Modified: Wed, May 9, 2012 5:59 PM



