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Sensors and Instrumentation and Nondestructive Evaluation

Biomedical Applications


 

Medical Ice Slurry Coolants for Inducing Targeted-Organ/Tissue Protective Cooling

by
Dr. Ken Kasza, P
hD et al. 

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Technology Description

Figure 1 shows a research version of the Argonne-developed system for making an ice slurry. The produced slurry has the following attributes:

  • Small ice particles (<0.1 millimeter),
  • High ice concentration (>50 weight percent),
  • Biologically compatible carrier liquid (saline solution plus other ingredients),
  • Several times the cooling capacity of water (ice = 80 cal/g°C versus water = 1 cal/g°C),
  • Excellent fluidity and storability obtained by altering ice particle size, shape, and surface roughness by using patented methods, and
  • Slurry that can be pumped nearly as easily as water through very small, properly designed delivery devices.

Argonne-Developed Equipment for Making and Delivering Medical SlurryFigure 1: Argonne-Developed Equipment for Making and Delivering Medical Slurry
Click on photo to view a larger image.

The slurry production equipment in Figure 1:

  • Produces slurry on-demand (< 2 min processing time),
  • Is portable,
  • Uses disposable sterile ingredient modules,
  • Has a controllable dose and delivery rate,
  • Is capable of continuous or intermittent delivery,
  • Can maintain protective cooling for > 2 hours, and
  • Includes special delivery injectors developed for various medical uses.

Medical Ice Slurry Coolants for Inducing Targeted-Organ/Tissue Protective Cooling
Next page: Application in Advanced Laparoscopic Procedures
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Multimedia

  • Laparoscopic Partial Nephrectomy with Ice Slurry as Coolant in the Porcine ModelLaparoscopic Partial Nephrectomy with Ice Slurry as Coolant in the Porcine Model
    This video depicts the usage of ice slurry cooling, using a porcine model, for protecting the kidney from ischemia damage during a partial nephrectomy. The video illustrates the ease of use, protective benefits and advantages of using slurry cooling over cold saline solution.
    Read full story and watch video
  • Computer model of a kidney being cooled by ice slurryComputer model of a kidney being cooled by ice slurry
    Computer model of a kidney being cooled by ice slurry (model created with ABAQUS code)
    Watch video

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Last Modified: Wed, May 9, 2012 6:14 PM

 

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